A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography – technologies that can illuminate life at the atomic scale.
The National Institutes of Health will provide $22.7 million over six years to create a national research and training hub at UW-Madison that will give scientists across the country access to this game-changing technology.
Cryo-electron microscopy (cryo-EM for short) is a method used to make images of biological molecules that are flash-frozen to capture them in their native state. No dyes or other alterations are needed to view the structures, which gives scientists a highly accurate picture of true biological function. Scientists can peer into the very surfaces where drugs and proteins interact, where diseases occur, and where viruses orchestrate their attacks. Cryo-EM has the